Research

V Foundation Grants 2011-Present

2012 Grants

2012 Designated Grants

Ramaswamy Govindan, M.D.
Siteman Cancer Center
Washington University in St. Louis
$50,000
Funded by UNICO in memory of Dorothy Jean Varsalona
Molecular Assay to Predict Outcomes in Resected NSCLC using Nanostring Technology

Steven Zeitels, M.D., FACS
Massachusetts General Hospital
$300,000
Funded by the 2011 Dick Vitale Gala
Voice Preservation in the Treatment of Early Glottic (Laryngeal) Cancer

Hai Yan, M.D., Ph.D.
Duke University Medical Center
$1,000,000
Supplemental SPORE
Funded by 2011 Wine Celebration and Accelerate Brain Cancer Cure
Developing Novel Approaches to Target Gliomas

Susan Goodin, PharmD.
Cancer Institute of New Jersey
$50,000
Funded by Marketing Research Consultants
Prevention of Prostate Cancer progression by atorvastatin and celecoxib

Peter Forsyth, M.D.
H. Lee Moffitt Cancer Center and Research Institute Foundation
$500,000
Funded by the 2011 Dick Vitale Gala
Developing Myxoma Virus as an Experimental Treatment for Brain Cancer Stem Cells in Children and Adults with Malignant Gliomas

MD Anderson Cancer Center
SPORE in Ovarian Cancer
$1,000,000
Funded by The Kay Yow Fund

Corrine Linardic, M.D., Ph.D.
Duke Children’s Hospital and Health Center
$50,000
Funded by Apple Gold
Understanding SFRP’s contribution to alveolar rhabdomyosarcoma tumorigenesis

Daniel S. Wechsler, M.D., Ph.D.
Duke University Medical Center
$150,000
Funded by Apple Gold
Strike While the Iron is Not:  Targeting CALM-Rearranged Leukemias by Iron Deprivation

St. Helena Hospital Foundation
$16,000
Funded by 2011 Wine Celebration
Caring for the Future

Victoria F. Borges, M.D., MSc
University of Colorado School of Medicine
$100,000
Funded by The Kay Yow Fund
Pilot Study the Prevention of Postpartum Pregnancy Associated Breast Cancer

Nehal Parikh, M.D.
Connecticut Children’s Medical Center
$100,000
Funded by ESPN
Isolation and Characterization of Cancer Stem Cells in Neuroblastoma Tumor Model 

All Children’s Hospital
Dick Vitale Pediatric Cancer Research Fellowship
$300,000
Funded by the 2011 Dick Vitale Gala

2011 GRANTS 

2011 V Scholars

Gang (Greg) Wang, Ph.D.
University of North Carolina at Chapel Hill
Lineberger Comprehensive Cancer Center
Chapel Hill, NC
Martin D. Abeloff, M.D. V Scholar Award*
Cancer Epigenetics:  Understanding Histone Methylation in Hematopoietic Malignancies

Hongwu Zheng, Ph.D.
Cold Spring Harbor Laboratory
Cold Spring Harbor, NY
Martin D. Abeloff, M.D. V Scholar Award*
Genetic and functional characterization of EGFR-targeted therapy resistance in malignant gliomas

*The research project that receives the highest rating by the Scientific Advisory Board will annually be designated as the Martin D. Abeloff, M.D. V Scholar Award.  This year we had two projects tied with the highest rating.

David Barbie, M.D.
Dana-Farber Cancer Institute
Boston, MA
Albert Wyrick V Scholar Award
Targeted Therapy Development for KRAS-Driven Lung Cancer
Funded by Michael and Carole Marks

Denise A. Chan, Ph.D.
University of California, San Francisco School of Medicine
San Francisco, CA
Defining the molecular mechanisms of metastasis and tumor recurrence following radiation therapy

Keith Syson Chan, Ph.D.
Dan L. Duncan Cancer Center at
Baylor College of Medicine
Houston, TX
Investigate the interplay between cellular differentiation status and oncogene-induced cancer phenotype
2011 JVCGC Volunteer Award
Funded in Honor of Dave Gibson and Felica Daniels

John T. Chang, M.D.
University of California, San Diego
Moores Cancer Center
La Jolla, CA
Modulating Polarity to Enhance CD8+ T Cell Immune Responses against Cancer

David Glenn DeNardo, Ph.D.
Washington University School of Medicine
Siteman Cancer Center
St. Louis, MO
Immune Regulation of the Cancer Stem Cell Niche

Geraldine J. Guasch, Ph.D.
Cincinnati Children’s Hospital Medical Center
Cincinnati, OH
Using a novel mouse model of transitional epithelial tumor to investigate cancer initiation and progression

Nada Y. Kalaany, Ph.D.
Children’s Hospital Boston
Boston, MA
Role of PTEN/P13K pathway in obesity-associated cancer incidence and progression
2011 Wine Celebration Vintner Grant
In Honor of Robin Baggett and Michelle Fields

Joseph W. Landry, Ph.D.
Virginia Commonwealth University
Massey Cancer Center
Richmond, VA
Chromatin Remodeling Complex NURF as Regulator of Cyclin D1 Transcription in Breast Cancer Cells

Tanja Mittag, Ph.D.
St. Jude Children’s Research Hospital
Memphis, TN
Multi-site Recognition of Ubiquitin Ligase Substrates in Signaling and Cancer

Trista E. North, Ph.D.
Beth Israel Deaconess Medical Center
Boston, MA
Characterization of Vitamin D3 as a novel regulator of hematopoietic stem cell homeostasis with therapeutic potential for leukemia treatment

Miles A. Pufall, Ph.D.
University of Iowa
Holden Comprehensive Cancer Center
Iowa City, IA
B-precursor acute lymphoblastic leukemia: Studying the mechanisms behind Dexamethasone and Prednisone sensitivity in high-risk patients

William L. Redmond, Ph.D.
Providence Portland Medical Center
Earle A. Chiles Research Institute
Portland, OR
Elucidate the mechanisms regulating prostate cancer immunotherapy

Zachary T. Schafer, Ph.D.
University of Notre Dame
Harper Cancer Research Institute
Notre Dame, IN
The Regulation of Tumor Cell Survival by Carcinoma-Associated Fibroblasts
Funded in Honor of Milly Longmire by Hooters of America

Qianben Wang, Ph.D.
Ohio State University
Comprehensive Cancer Center
Columbus, OH
Targeting aberrant FoxA1-CREB1 signaling in castration-resistant prostate cancer

Bin Zheng, Ph.D.
Columbia University Medical Center
New York, NY
Targeting Metabolism in Melanoma

2011 Designated Grants

Gary Hammer, M.D., Ph.D.
University of Michigan Comprehensive Cancer Center
Ann Arbor, MI
Genomic Analyses of Adrenocortical Cancer

Chunyan He, ScD
Indiana University
Simon Cancer Center
Indianapolis, IN
Genetic Variants, microRNA Expression and Breast Cancer
Funded by the Kay Yow Cancer Fund

Hanlee Ji, M.D.
James M. Ford, M.D.
Stanford Genome Technology Center
Palo Alto, CA
Computational Analysis of Gastric Cancer Genomes and Inherited Gastric Cancer
Funded by the Gastric Cancer Fund

Mark Kester, Ph.D.
Kevin Stavely-O’Carroll, M.D., Ph.D.
Penn State University Cancer Center
Hershey, PA
Novel Therapeutic Approaches to Gastrointestinal Malignancies
Funded by UNICO Foundation
In Memory of Salvatore Bernardi

St. Helena Hospital
St. Helena, CA
Caring for Future

 2011 Translational Grants

Suzanne J. Baker, Ph.D. 
Cynthia Wetmore, M.D., Ph.D. 
St. Jude Children’s Research Hospital 
Memphis, TN 
Targeting PDGFR in Pediatric High-Grade Gliomas

Andrei Thomas-Tikhonenko, Ph.D.
Stephan Grupp, M.D., Ph.D.
Children’s Hospital of Philadelphia
Philadelphia, PA
Novel therapeutic targets in acute B-lymphoblastic leukemia

Richard Roden, Ph.D.
Sara Pai, M.D., Ph.D.
TC Wu, M.D., Ph.D.
Johns Hopkins University School of Medicine
Baltimore, MD
Treatment of Head and Neck cancer with an HPV vaccine

Iannis Aifantis, Ph.D.
Elizabeth A. Raetz, M.D.
New York University School of Medicine
New York, NY
Clinical Implications of TET Regulated DNA Methylation in Acute Lymphoblastic Leukemia

Leonard I. Zon, Ph.D.
Richard M. White, M.D.
Children’s Hospital Boston
Boston, MA
Cell Fate as a Target in Melanoma

Janice M. Mehnert, M.D.
Eileen P. White, Ph.D.
Cancer Institute of New Jersey
New Brunswick, NJ
Examining the Role of Autophagy in Melanoma Tumorigenesis

Fatih M. Uckun, M.D., Ph.D.
Paul S. Gaynon, M.D.
Amanda M. Termuhlen, M.D.
Childrens Center for Cancer and Blood Diseases
Children’s Hospital Los Angeles
Los Angeles, CA
Funded by The V Foundation Wine Celebration
Directing Leukemia Cells to Self-Destruct Using Recombinant Human CD19-Ligand:sTrial Fusion Protein

Carlos A. Ramos, M.D.
Ann M. Leen, Ph.D.
Dan L. Duncan Cancer Center at Baylor College of Medicine
Houston, TX
Most Closely HLA-Matched Allogeneic LMP1/2 – Specified Cytotoxic T Lymphocytes for Treatment of Patients
with Relapsed Epstein-Barr Virus-Associated Lymphomas

Hua Eleanor Yu, Ph.D.
Stephen J. Forman, M.D.
Marcin Kortylewski, Ph.D.
Beckman Research Institute of the City of Hope
Duarte, CA
Targeting STAT3 in tumor and the tumor microenvironment by a novel siRNA technology to treat lymphoma
Funded by The V Foundation Wine Celebration in Honor of Neil Aldoroty