Professor and Head

Department of Biopharmaceutical Sciences
University of Illinois at Chicago
Chicago IL

Research Interests:

• Molecular pharmacology and genetics of anticancer drug action and tumor cell drug resistance

• Molecular mechanisms of regulation of genes associated with multidrug resistance in cancer (topoisomerases, MDR1, MRP)

• Action of and tumor cell resistance to inhibitors of the DNA topoisomerases

• Post-translational modifications of proteins

• Pharmacogenomics

• Role of splice variants in anticancer drug responsiveness