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The V Foundation Awards 2011 V Scholars

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The V Foundation for Cancer Research, one of the nation’s leading cancer research fundraising organizations, announced today that seventeen physicians/scientists across the United States have been awarded two-year, $200,000 grants through the 2011 V Scholar program. The $3.4 million in funding given through the V Scholar program is an integral part of The V Foundation’s grant initiatives that funds young scientists as they begin their career in cancer research. This funding, given to researchers across eleven different states, is continually bringing science closer to finding a cure for cancer.

V Scholar grants were awarded to each of these promising individuals through a competitive process managed by The V Foundation’s Scientific Advisory Board. This allows the V Scholar to decide the best means for using the funding in his or her research project.

“Each year, the V Scholars are selected from a group of young cancer scientists that includes the most outstanding candidate from each of the National Cancer Institute designated cancer centers,” said Robert C. Bast, Jr., M.D., Vice President for Translational Research at M.D. Anderson Cancer Center and a member of the Scientific Advisory Board. This year the V Scholars are even more exceptional than in the past.”

Each year, The V Foundation’s Scientific Advisory Board selects an outstanding project to award in honor of Martin Abeloff, a former Scientific Advisory Board member. This year, having received two outstanding proposals, the Martin D. Abeloff Scholar Award will go to two V Scholar researchers: Greg Wang from the Lineberger Comprehensive Cancer Center in Chapel Hill, N.C., and Hongwu Zheng from the Cold Spring Harbor Laboratory in Cold Spring Harbor, N.Y.

For more information on The V Foundation, please log onto www.jimmyv.org or call 1-800-4JimmyV. You can also visit Twitter.com/TheVFoundation or Facebook.com/VFoundation to learn more.

Editors Note: A complete list of the 2011 V Foundation grant recipients follows.

Martin D. Abeloff, M.D. V Scholar Award*

Gang (Greg) Wang, Ph.D.
University of North Carolina at Chapel Hill
Lineberger Comprehensive Cancer Center
Chapel Hill, NC
Cancer Epigenetics: Understanding Histone Methylation in Hematopoietic Malignancies

Hongwu Zheng, Ph.D.
Cold Spring Harbor Laboratory
Cold Spring Harbor, NY
Genetic and functional characterization of EGFR-targeted therapy resistance in malignant gliomas

Albert Wyrick V Scholar Award

David Barbie, M.D.
Dana-Farber Cancer Institute
Boston, MA
Targeted Therapy Development for KRAS-Driven Lung Cancer
Funded by Michael and Carole Marks

V Foundation V Scholars

Denise A. Chan, Ph.D.
University of California, San Francisco School of Medicine
San Francisco, CA
Defining the molecular mechanisms of metastasis and tumor recurrence following radiation therapy

Keith Syson Chan, Ph.D.
Dan L. Duncan Cancer Center at
Baylor College of Medicine
Houston, TX
Investigate the interplay between cellular differentiation status and oncogene-induced cancer phenotype
2011 JVCGC Volunteer Award
Funded in Honor of Dave Gibson and Felica Daniels

John T. Chang, M.D.
University of California, San Diego
Moores Cancer Center
La Jolla, CA
Modulating Polarity to Enhance CD8+ T Cell Immune Response against Cancer

David Glenn DeNardo, Ph.D.
Washington University School of Medicine
Siteman Cancer Center
St. Louis, MO
Immune Regulation of the Cancer Stem Cell Niche

Geraldine J. Guasch, Ph.D.
Cincinnati Children’s Hospital Medical Center
Cincinnati, OH
Using a novel mouse model of transitional epithelial tumor to investigate cancer initiation and progression

Nada Y. Kalaany, Ph.D.
Children’s Hospital Boston
Boston, MA
Role of PTEN/P13K pathway in obesity-associated cancer incidence and progression
2011 Wine Celebration Vintner Grant
In Honor of Robin Baggett and Michelle Fields

Joseph W. Landry, Ph.D.
Virginia Commonwealth University
Massey Cancer Center
Richmond, VA
Chromatin Remodeling Complex NURF as Regulator of Cyclin D1 Transcription in Breast Cancer Cells

Tanja Mittag, Ph.D.
St. Jude Children’s Research Hospital
Memphis, TN
Multi-site Recognition of Ubiquitin Ligase Substrates in Signaling and Cancer

Trista E. North, Ph.D.
Beth Israel Deaconess Medical Center
Boston, MA
Characterization of Vitamin D3 as a novel regulator of hematopoietic stem cell homeostasis with therapeutic potential for leukemia treatment

Miles A. Pufall, Ph.D.
University of Iowa
Holden Comprehensive Cancer Center
Iowa City, IA
B-precursor acute lymphoblastic leukemia: Studying the mechanisms behind Dexamethasone and Prednisone sensitivity in high-risk patients

William L. Redmond, Ph.D.
Providence Portland Medical Center
Portland, OR
Elucidate the mechanisms regulating prostate cancer immunotherapy

Zachary T. Schafer, Ph.D.
Harper Cancer Research Institute
South Bend, IN
The Regulation of Tumor Cell Survival by Carcinoma-Associated Fibroblasts

Qianben Wang, Ph.D.
Ohio State University
Comprehensive Cancer Center
Columbus, OH
Targeting aberrant FoxA1-CREB1 signaling in castration-resistant prostate cancer

Bin Zheng, Ph.D.
Columbia University Medical Center
New York, NY
Targeting Metabolism in Melanoma